The rise in opioid-related cardiac arrests during the study period was significant. By 2018, opioids were related to a similar number of cardiac arrests as all other reasons put together
Senada S. Malik
Of 1,410,475 cardiac arrest hospitalisations, 43,090 (3.1%) occurred in opioid users. The rate of in-hospital mortality in cardiac arrest patients with and without opioid use was 56.7% versus 61.2%, respectively. However, in an analysis adjusted for several factors including liver disease, atrial fibrillation and renal failure, there was no difference in the risk of mortality between cardiac arrest patients with or without opioid abuse (odds ratio 0.96; 95% confidence interval 0.92–1.01; p=0.15). Opioid users had higher rates of alcohol abuse (16.9% vs. 7.1%; p<0.05), depression (18.8% vs. 9%; p<0.05) and smoking (37.0% vs. 21.8%; p<0.05) compared to those not using opioids.
The study found a significant increasing trend in opioid-associated cardiac arrest over the seven-year period (p for trend <0.05). Study author Ms. Senada S. Malik, a medical researcher at the University of New England, Biddeford, US said: “The rise in opioid-related cardiac arrests during the study period was significant. By 2018, opioids were related to a similar number of cardiac arrests as all other reasons put together.” She continued: “This was an observational study so we cannot conclude causality, but the findings do suggest that the opioid epidemic in the US may have contributed to an increasing number of cardiac arrests.”
Source: Healthcare in Europe